Alzheimer's blood test

Family, Education, Health and Pets
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Alzheimer’s blood test catches 90% of early dementia cases, study finds

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To be honest, not sure if I want to know as there is limited medication right now.

Other than making sure your affairs are in order, which is recommended anyway, not sure what benefit this has right now?

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But there’s no treatment, it would just give me anxiety if I knew I was predestined to get this horrible condition

European Medicines Agency (EMA) has rejected a licence for an Alzheimer’s treatment which slows cognitive decline.

The EMA said the benefits of lecanemab did not counterbalance the risk of serious side effects, especially bleeding and swelling in the brain.

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The few medicaments for AD are incredibly expensive and have not thrilled with their results. In the early 90s, I started working with scientists trying to develop treatments. Things have not progressed very far since then. >30 years, and almost no progress.

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Funny, I’ve watched some material recently about AD. The scientists highlighted that the bad protein is removed from the brain during a deep sleep. My takeaway is to take sleep hygiene seriously, best medicine I’ve ever herd off :grin:

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The lack of progress is not surprising as they all concentrate on removing the typical brain plaques although they may be symptoms not a cause.

To be fair there is little else to focus on.

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Another small study which may prove promising.

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Info coming thick and fast atm.

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A new study " SGLT-2 inhibitors might prevent dementia"

SGLT2 inhibitors are a class of prescription medicines that are FDA-approved for use with diet and exercise to lower blood sugar in adults with type 2 diabetes

  • This large population based cohort study among people with type 2 diabetes aged 40-69 years found a 35% lower risk of dementia associated with use of SGLT-2 inhibitors compared with DPP-4 inhibitors

  • This finding persisted regardless of dementia type and across subgroups of diverse population characteristics such as age, sex, concomitant use of metformin, and baseline cardiovascular risk.

  • Please note that Type 2 diabetes substantially predisposes people to Alzheimer’s disease and vascular dementia through multiple pathways so giving this treatment to people who do not have Type 2 may not reduce the risk of dementia

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