Ritalin 70 years (1944-ish)... studies and research started in the 1950's
Concerta is slow release, while possessing the same ingredient as Ritalin, it has other chemicals added to ration out the methylphenidate... which means to me the uptake is in the intestines not in the stomach.
Short-Term Effects
The effects of Ritalin, both adverse and desired, are similar to the effects of amphetamines.
Low doses
Appetite suppression
Wakefulness
Heightened alertness
Euphoria 21
Impairment of voluntary movement
Headache
Irregular or rapid heartbeat
Nausea and vomiting
Skin rash
Some people may experience drowsiness 22
High doses
Exhilaration and excitation
Agitation
Muscle twitching
Dilation of pupils
Confusion
Hallucinations and paranoia
Flushing
Increased blood pressure and pulse rate
Dry mouth
Vomiting
Fever and sweating
Delirium
Seizures, followed by coma 23
Anxiety and restlessness
Excessive repetition of movements and meaningless tasks
Formication- the sensation of bugs or worms crawling under the skin 24
Long-Term Effects
The long-term effects of therapeutic doses of Ritalin are not clearly known. Some studies have shown long-term use of Ritalin may suppress growth in both height and weight, while other studies contradict this finding. Minor growth suppression and weight loss does occur in children under long-term psychostimulant treatment, but some have suggested that weight loss may be more common in children who weigh more than the average for their height before they begin taking Ritalin, and growth deficits may be partly related to ADHD rather than the medication.
So my side effects with Ritalin, slight nausea, loss of appetite, dry mouth, rollercoaster emotions, numb manly bits and loss of libido, ruminating and severe depression between doses... last dose at 1400, then restless sleep, waking to urinate 2 to 3x a night.
If there was a noticeable improvement of concentration, I could try to live with the other side effects... well that loss of my manly bits is not something I'll live with for a gain in concentration... maybe when I'm 80 that loss will be ok.
The Focalin xr... was good the first day, as all I had was dry mouth and nausea, no rollercoaster emotions... slight restless sleep... each days following dose, changed me completely into a zombie.. nothing was sharp in my vision, always foggy blur in the periphery, nothing was funny, exciting or laughable, manly bits were gone, hunger came at 6pm but the food was tasteless and unsatisfying... nausea and severe dry mouth and mouth sores and really restless sleep and having to urinate 3 to 4x a night... oh and my concentration factor was blown out of the water... way less than without meds.
I told the doc yesterday all this, and she suggested concerta... I said don't want to experiment with any more meds for a couple weeks... from all the reading I've done, it seems that I must be one of the 30% that anything with methylphenidate does not help concentration and only suffer side effects.
I would be willing to try Adderall, as it is a different molecular makeup of amphetamines... oh the the other thing about Switzerland that just seems stupid... a "pharmacist" can't dose out 7 or 10 units for a trial... they give you a bottle of 30... in the states, a doctor writes an rx and says 5 tabs, the pharmacist dispenses 5 tabs.
I'm reading up on St. Johnswort, Eleuthero, Ginkgo biloba and amino acids to increase dopamine and reuptake inhibitors of both dopamine and NE...
there has to be a better solution with less negative side effects.